Here is a very comprehensive list of research articles, abstracts, news stories and other references about cannabis and heart disease. These links are listed under ‘Heart Disease / Cardiovascular’ in Granny Storm Crow’s MMJ Reference List. The author, Granny Storm Crow, has spent the better part of a lifetime collecting and sharing objective cannabis research and information. In her own words:
“It is time for us to demand a change in the laws on cannabis! We must keep telling the truth, keep presenting the facts to our friends and our families. The facts are there in PubMed- cannabis IS medicine! Our government lies to us about cannabis! And folks-
If the truth won’t do, then something is wrong!” – Granny Storm Crow
Cannabis and Heart Disease Links from Granny Storm Crow’s MMJ Reference List
Cannabis and Heart Disease Articles
- Intravenous delta9-Tetrahydrocannabinol: Effects of ventilatory control and cardiovascular dynamics (full – 1975)
- The Effects of Delta-9-Tetrahydrocannabinol (Cannabis) on Cardiac Performance with and without Beta Blockade (full – 1976)
- The cardiovascular effects of marihuana in man (full – 1977)
- Short-term effects of smoked marihuana on left ventricular function in man (full – 1977)
- Cannabinoids. II. Cardiovascular Effects (full – 1980)
- Cannabinoid-Induced Hypotension and Bradycardia in Rats Is Mediated by CB1-Like Cannabinoid Receptors (full – 1997)
- Endogenous cannabinoids mediate hypotension after experimental myocardial infarction (full – 2001)
- Mechanisms of anandamide-induced vasorelaxation in rat isolated coronary arteries (full – 2001)
- Influence of the CB1 receptor antagonist, AM 251, on the regional haemodynamic effects of WIN-55212-2 or HU 210 in conscious rats (full – 2002)
- Endocannabinoids are implicated in the infarct size-reducing effect conferred by heat stress preconditioning in isolated rat hearts. (full – 2002)
- Estrogen stimulates arachidonoylethanolamide release from human endothelial cells and platelet activation (full – 2002)
- Endocannabinoids protect the rat isolated heart against ischaemia (full – 2003)
- Vasodilator actions of abnormal-cannabidiol in rat isolated small mesenteric artery (full – 2003)
- CB1 cannabinoid receptor antagonism promotes remodeling and cannabinoid treatment prevents endothelial dysfunction and hypotension in rats with myocardial infarction (full – 2003)
- Cannabinoid CB2 receptor activation reduces mouse myocardial ischemia-reperfusion injury: involvement of cytokine/chemokines and PMN (full – 2003)
- A new endothelial target for cannabinoids (full – 2003)
- Endocannabinoids as mediators in the heart: a potential target for therapy of remodelling after myocardial infarction? (full – 2003)
- Endocannabinoids Acting at Cannabinoid-1 Receptors Regulate Cardiovascular Function in Hypertension (full – 2004)
- The complexities of the cardiovascular actions of cannabinoids (full – 2004)
- Cardiovascular Pharmacology of Cannabinoids (full – 2005)
- Anandamide reduces infarct size in rat isolated hearts subjected to ischaemia–reperfusion by a novel cannabinoid mechanism (full – 2005)
- Effects of AM281, a cannabinoid antagonist, on systemic haemodynamics, internal carotid artery blood flow and mortality in septic shock in rats (full – 2005)
- The cardiovascular actions of anandamide: more targets? (full – 2005)
- Further Characterization of the Time-Dependent Vascular Effects of Δ9-Tetrahydrocannabinol (full – 2006)
- Illicit Drug Use in Young Adults and Subsequent Decline in General Health: The Coronary Artery Risk Development in Young Adults (CARDIA) Study (full – 2006)
- Signaling pathways involved in the cardioprotective effects of cannabinoids. (full – 2006)
- Does Cannabis Hold the Key to Treating Cardiometabolic Disease (full – 2006)
- The in vitro and in vivo cardiovascular effects of {Delta}9-tetrahydrocannabinol (THC) in rats made hypertensive by chronic inhibition of nitric oxide synthase (full – 2007)
- Characterization of the vasorelaxant mechanisms of the endocannabinoid anandamide in rat aorta (full – 2007)
- The novel endocannabinoid receptor GPR55 is activated by atypical cannabinoids but does not mediate their vasodilator effects. (full – 2007)
- Endocannabinoids acting at CB1 receptors mediate the cardiac contractile dysfunction in vivo in cirrhotic rats (full – 2007)
- Endocannabinoids and the haematological system (full – 2007)
- Cannabinoids and cardiovascular disease: a tale of passions and illusions. (full – 2007)
- Cannabidiol , a nonpsychoactive Cannabis constituent, protects against myocardial ischemic reperfusion injury. (full – 2007)
- Cardiovascular effects of cannabinoids in conscious spontaneously hypertensive rats (full – 2007)
- The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: Δ9-tetrahydrocannabinol, cannabidiol and Δ9-tetrahydrocannabivarin (full – 2008)
- Cannabinoid receptors in acute and chronic complications of atherosclerosis (full – 2008)
- The Endocannabinoid System and Cardiovascular Disease – Introduction (full – 2008)
- Endocannabinoids and Liver Disease. V. Endocannabinoids as mediators of vascular and cardiac abnormalities in cirrhosis (full – 2008)
- CB1 Cannabinoid Receptor Inhibition: Promising Approach for Heart Failure? (full – 2008)
- Modulation of the Endocannabinoid System in Cardiovascular Disease (full – 2008)
- Acute hypertension reveals depressor and vasodilator effects of cannabinoids in conscious rats (full – 2008)
- Endocannabinoids and cannabinoid receptors in ischaemia–reperfusion injury and preconditioning (full – 2008)
- Endocannabinoids, blood pressure and the human heart (full – 2008)
- Function of cannabinoids in heart failure (full – 2008)
- The endocannabinoid system: an osteopathic perspective (full – 2008)
- Endocannabinoids and the Heart (full – 2009)
- The emerging role of the endocannabinoid system in cardiovascular disease (full – 2009)
- Endocannabinoids and cardiac contractile function: pathophysiological implications (full – 2009)
- Acute administration of cannabidiol in vivo suppresses ischaemia-induced cardiac arrhythmias and reduces infarct size when given at reperfusion (full – 2010)
- The cardiac and haemostatic effects of dietary hempseed (full – 2010)
- Endogenous cannabinoid signaling is essential for stress adaptation (full – 2010)
- US Patent Application 20100158973 – THERAPEUTIC USES OF CANNABIDIOL COMPOUNDS (full – 2010)
- The potential for clinical use of cannabinoids in treatment of cardiovascular diseases (full – 2011)
- Endocannabinoid system in cardiovascular disorders – new pharmacotherapeutic opportunities (full – 2011)
- Acute administration of cannabidiol in vivo suppresses ischaemia-induced cardiac arrhythmias and reduces infarct size when given at reperfusion (full – 2011)
Cannabis and Heart Disease Abstracts
- Propranolol Effects on Acute Marihuana Intoxication in Man (abst – 1977)
- The cardiovascular and autonomic effects of repeated administration of delta-9-tetrahydrocannabinol to rhesus monkeys (abst – 1981)
- Effects of acute marijuana smoking in post-menopausal women (abst – 1986)
- The inhibitory effects of cannabinoids, the active constituents of Cannabis sativa L. on human and rabbit platelet aggregation (abst – 1989)
- Changes in middle cerebral artery velocity after marijuana (abst – 1992)
- Development of HU-211 as a neuroprotectant for ischemic brain damage (abst – 1995)
- Cardiovascular effects of endocannabinoids–the plot thickens (abst – 2000)
- Involvement of central and peripheral cannabinoid receptors in the regulation of heart resistance to arrhythmogenic effects of epinephrine (abst – 2000)
- Endogenous cannabinoid anandamide increases heart resistance to arrhythmogenic effects of epinephrine: role of CB(1) and CB(2) receptors (abst – 2001)
- Activation of cannabinoid receptors decreases the area of ischemic myocardial necrosis (abst – 2002)
- Increase of the heart arrhythmogenic resistance and decrease of the myocardial necrosis zone during activation of cannabinoid receptors (abst – 2002)
- Endogenous cannabinoids improve myocardial resistance to arrhythmogenic effects of coronary occlusion and reperfusion: a possible mechanism (abst – 2002)
- Cardiac and vascular effects of cannabinoids: toward a therapeutic use? (abst – 2005)
- CARDIOVASCULAR Effects of AM281, a cannabinoid antagonist, on systemic haemodynamics, internal carotid artery blood flow and mortality in septic shock in rats (abst – 2005)
- Influence of Anandamide, the Endogenous Agonist of Cannabinoid Receptors on the Circulatory System (abst – 2005)
- The endogenous cardiac cannabinoid system: a new protective mechanism against myocardial ischemia (abst – 2006)
- Delta-9-tetrahydrocannabinol protects cardiac cells from hypoxia via CB2 receptor activation and nitric oxide production (abst – 2006)
- Marijuana use, diet, body mass index, and cardiovascular risk factors (abst – 2006)
- Cannabinoids and cardiovascular disease: the outlook for clinical treatments (abst – 2007)
- Cannabinoids as therapeutic agents in cardiovascular disease (abst – 2007)
- Dexanabinol prevents development of vasospasm in the rat femoral artery model (abst – 2008)
- Time-dependent vascular actions of cannabidiol in the rat aorta (abst – 2009)
- Cannabidiol Attenuates Myocardial Dysfunction, Fibrosis, Inflammation, Cell Death and Interrelated Signaling Pathways Associated With Diabetic Cardiomyopathy (abst – 2009)
- Endocannabinoids and cardiovascular prevention: real progress? (abst – 2009)
- CB2 cannabinoid receptor activation is cardioprotective in a mouse model of ischemia/reperfusion (abst – 2009)
- Cannabinoids and atherosclerosis (abst – 2009)
- Substantially altered expression pattern of cannabinoid receptor 2 and activated endocannabinoid system in patients with severe heart failure (abst – 2010)
- Pharmacologically induced hypothermia with cannabinoid receptor agonist WIN55, 212-2 after cardiopulmonary resuscitation (abst – 2010)
- Acute administration of cannabidiol in vivo suppresses ischaemia-induced cardiac arrhythmias and reduces infarct size when given at reperfusion (abst – 2010)
- Interaction between anandamide and sphingosine-1-phosphate in mediating vasorelaxation in rat coronary artery (abst – 2010)
- Cannabidiol as an anti-arrhythmic, the role of the CB1 receptors (abst – 2011)
- Distinctive effects of plant protein sources on renal disease progression and associated cardiac hypertrophy in experimental kidney disease (abst – 2011)
- Deficiency of type 1 cannabinoid receptors worsens acute heart failure induced by pressure overload in mice (abst – 2011)
- The effects of hempseed meal intake and linoleic acid on Drosophila models of neurodegenerative diseases and hypercholesterolemia (abst – 2011)
- Cannabinoid/agonist Win 55,212-2 reduces cardiac ischaemia-reperfusion injury in zucker diabetic fatty rats: role of cb2 receptors and cardiac inos/enos expression (abst – 2011)
- Effect of substance abuse on defibrillation threshold in patients with implantable cardioverter-defibrillator (abst – 2011)
- Endocannabinoids and the cardiovascular response to stress (abst – 2011)
- Cardiotoxicity associated with the synthetic cannabinoid, K9, with laboratory confirmation (abst – 2011)
- Effects of intracisternal administration of cannabidiol on the cardiovascular and behavioral responses to acute restraint stress (abst – 2011)
- The effect of dietary hempseed on atherogenesis and contractile function in aortae from hypercholesterolemic rabbits (abst – 2011)
- Targeting the Endocannabinod System to Limit Myocardial and Cerebral Ischemic and Reperfusion Injury (abst – 2011)
- Cannabidiol (CBD) as an Anti-Arrhythmic – the Role of the CB1 Receptors (abst – 2011)
Cannabis and Heart Disease News and Other References
- Effects of cannabis roots on the heart (forum post- letter – 1973)
- Cannabinoids prevented the development of heart failure in animal study (news – 2003)
- Cardiovascular Effects of Cannabis (news – 2003?)
- Medical Biology: Marijuana and the Heart (news – 2005)
- Marijuana Chemical Fights Hardened Arteries (news – 2005)
- Medical marijuana: study shows that THC slows atherosclerosis (news – 2005)
- Cannabis chemical ‘helps heart’ (news – 2005)
- Cannabis use not associated with risk factors for diseases of heart and circulation (news – 2006)
- THC protects heart cells in the case of lowered oxygen supply (news – 2006)
- Cannabinoid Offers Cardioprotection (news – 2006)
- Heavy Cannabis Use Not Independently Associated With Cardiovascular Risks (news – 2006)
- Rimonabant doesn’t reduce heart risk (news – 2008)
- Lab Notes: Pot Has Benefits for Diabetic Hearts (news – 2010)
- Inhaled Incense “K2” May Cause Heart Damage (news – 2010)
- Cannabidiol (CBD) as an Anti-Arrhythmic – the Role of the CB1 Receptors (news – 2010)
- Pot Compound Mitigates Diabetic Cardiomyopathy (news – 2010)
- Marijuana Compounds Hold Promise In Treatment Of Cardiovascular Diseases (news – 2011)
Other Weedist Granny Storm Crow Links
- Cannabis and Driving | Granny Storm Crow’s MMJ Reference
- Cannabis and Nausea | Granny Storm Crow’s MMJ Reference
- Cannabis and Lung Cancer | Granny Storm Crow’s MMJ Reference
- Cannabis and Addiction | Granny Storm Crow’s MMJ Reference
- Granny Storm Crow’s List Archives
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